COMPARISON OF LAPAROSCOPIC SALINE INFUSED TO DRY RADIO FREQUENCY ABLATION OF RENAL TISSUE: EVOLUTION OF HISTOLOGICAL INFARCT IN THE PORCINE MODEL

Abstract

The effects of RFA of renal tissue has 2 phases, namely initial direct thermal ablation causing acute cell death and a later subacute phase causing subsequent infarction of the distal arterial vascular supply to the ablated region, resulting in more cell death and coagulative necrosis. Glomeruli are the last structures to lose viability in necrotic areas. Most importantly cellular death caused by RFA is permanent.