Comparison of Pharmacodynamic and Pharmacokinetic Indices of Efficacy for 5 Fluoroquinolones toward Pathogens of Dogs and Cats

Abstract

E. coli resistance to fluoroquinolones approximated 40%. For susceptible isolates, enrofloxacin, marbofloxacin, and ciprofloxacin more consistently reached indices associated with predicted efficacy, but only at the high dose.