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Catalyst-free synthesis of quinazolin-4-ones from (hetero)aryl-guanidines: application to the synthesis of pyrazolo[4,3-f]quinazolin-9-ones, a new family of DYRK1A inhibitors

New FamilyEngineeringMedicineDrug DiscoveryOrganic ChemistryCatalyst-free SynthesisHeterocycle ChemistryPharmacologyDyrk1a InhibitorsSynthetic ChemistryBiomolecular Engineering