?‐MANNOSIDASE DEFICIENCY IN ANGLO NUBIAN GOATS

Abstract

SUMMARY Two newly‐born Anglo Nubian kids with clinical evidence of a severe neurological condition were examined. Pathological examination revealed extensive cytoplasmic vacuolation in neural tissue and in localised areas in the kidney, pancreas and lymphoid tissue. Biochemical investigations demonstrated a deficiency of ?T‐mannosidase in tissues and blood serum.