The Safety and Efficacy of Intrathecal Adenosine in Patients with Chronic Neuropathic Pain

Abstract

This is the first series of patients with chronic neuropathic pain in which tolerability to spinal adenosine administration has been evaluated. A subset of patients reported transient low back pain as the only side effect. Spontaneous and evoked pain intensity decreased in most patients, an effect lasting for a median of 24 h.