An ontology of scientific experiments

Larisa Soldatova, Ross D. King

Journal of The Royal Society Interface · 2006 · 215 citations · 6 references

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TL;DR

Scientific experiments require formal descriptions for efficient analysis, annotation, and sharing, yet no general ontology exists despite several subject‑specific ones. The authors propose EXPO, a general ontology of experiments, to fill this gap. EXPO connects the SUMO upper ontology to subject‑specific experiment ontologies by formalizing generic concepts of design, methodology, and results in OWL‑DL, and is illustrated with high‑energy physics and phylogenetics case studies. Applying EXPO clarified experiment goals and structure, exposed ambiguities, revealed an unexpected similarity, and demonstrates its general value for formalizing science.

Abstract

The formal description of experiments for efficient analysis, annotation and sharing of results is a fundamental part of the practice of science. Ontologies are required to achieve this objective. A few subject-specific ontologies of experiments currently exist. However, despite the unity of scientific experimentation, no general ontology of experiments exists. We propose the ontology EXPO to meet this need. EXPO links the SUMO (the Suggested Upper Merged Ontology) with subject-specific ontologies of experiments by formalizing the generic concepts of experimental design, methodology and results representation. EXPO is expressed in the W3C standard ontology language OWL-DL. We demonstrate the utility of EXPO and its ability to describe different experimental domains, by applying it to two experiments: one in high-energy physics and the other in phylogenetics. The use of EXPO made the goals and structure of these experiments more explicit, revealed ambiguities, and highlighted an unexpected similarity. We conclude that, EXPO is of general value in describing experiments and a step towards the formalization of science.

References

6