British journal of surgery · 1995 · 118 citations · 25 references
MedicineClinical SciencesSurgeryBowel ManagementGastroenterologyGeneral SurgeryBowel ObstructionColorectal SurgeryConstipation ManagementEnema UseIntestinal ObstructionLaxative TherapyChronic Constipation TreatmentColonic InertiaColonic Transit TimeConstipation TransitElective ColectomyPuborectalis Muscle
The aim of this study was to conduct a prospective assessment of the results of total abdominal colectomy and ileorectal anastomosis (TAC) in patients with colonic inertia. Overall, 416 patients were evaluated for chronic constipation. Of the patients 54 (13 per cent) had colonic inertia, defined as diffuse marker delay during transit study without paradoxical puborectalis contraction on cinedefaecography or electromyography. All 54 patients (42 women and 12 men), with a mean age of 49 (range 17-78) years, underwent TAC. Preoperative bowel frequency was a mean of one every 8 days, requiring large doses of laxatives, enemas or both. There was no major postoperative morbidity; five patients were readmitted due to bowel obstruction, three for successful conservative management while the other two required enterolysis. After a mean follow-up of 27 (range 2-51) months these 54 patients reported a mean frequency of spontaneous bowel movements of 3.7 (range 1-10) per day. 'Excellent' or 'good' outcome was reported by 51 patients (94 per cent). TAC can be performed with acceptable morbidity and 94 per cent of patients will have satisfactory improvement in bowel habit.
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Simplified assessment of segmental colonic transit
Amanda M. Metcalf, Sidney F. Phillips, Alan R. Zinsmeister et al. · Gastroenterology · 1987 · 936 citations
A new method for studying gut transit times using radioopaque markers
John Hinton, J E Lennard‐Jones, Aneurin Young · Gut · 1969 · 836 citations · Full text
Segmental colonic transit time
Pierre Arhan, Ghislain Devroede, B Jéhannin et al. · Diseases of the Colon & Rectum · 1981 · 475 citations
Medicine, Pediatrics, Radiology +16
Severe chronic constipation of young women: 'idiopathic slow transit constipation'.
D M Preston, J E Lennard‐Jones · Gut · 1986 · 411 citations · Full text