Detection of Helicobacter pylori and Determination of Clarithromycin Susceptibility Using Formalin-Fixed, Paraffin-Embedded Gastric Biopsy Specimens by Fluorescence In Situ Hybridization

Abstract

FISH results correlated well with H. pylori infection and were able to identify clarithromycin-susceptible and -resistant strains. This technique will be helpful in determining the bacterial density and the success of treatment where clarithromycin has been widely used in populations to increase the efficacy of the treatment and to clarify the treatment failure in vitro.