Proteomic Analysis of Uveal Melanoma Reveals Novel Potential Markers Involved in Tumor Progression

Abstract

Tumor progression and development of metastases is a multicomplex system. Comparing protein expression in two cell lines derived from metastases with a cell line derived from a primary uveal melanoma from the same patient identified proteins involved in tumor progression, and proteins specifically expressed in the metastases, which have the potential of becoming clinically useful biomarkers.