PHOTOSENSITIVITY DUE TO HYDROCHLOROTHIAZIDE

Abstract

ABSTRACT A case of photosensitivity induced by only 2 tablets of hydrochlorothiazide (Behyd‐RA tablets) is reported. The patient had sunburn‐like eruptions on the face, neck, arms and hands. The histologic picture was the same as in polymorphic light eruption. Black light irradiation could induce the same reaction clinically as well as histologically. The patient had an identical history five years previously. A rapid improvement of the lesions occurred after cessation of the hydrochlorothiazide administration and avoidance of exposure to sunlight. No photosensitive reactions have been noted since. The skin reaction of this case was due to long ultraviolet light and hydrochlorothiazide, and possibly photoallergic in nature.