Mechanisms of Disease: role of chondrocytes in the pathogenesis of osteoarthritis—structure, chaos and senescence

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S.S. Glasson, Roger Askew, Barbara Sheppard et al. · Nature · 2005 · 1.3K citations

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Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage.

R. Clark Billinghurst, Leif Dahlberg, Mirela Ionescu et al. · Journal of Clinical Investigation · 1997 · 975 citations · Full text

Medicine, Orthopaedic Surgery, Pathology +14

Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage.

Peter G. Mitchell, Holly A. Magna, Lucy Reeves et al. · Journal of Clinical Investigation · 1996 · 943 citations · Full text

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ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro

Heather Stanton, Fraser M. Rogerson, Charlotte J. East et al. · Nature · 2005 · 915 citations

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Osteoarthritis chondrocytes die by apoptosis: A possible pathway for osteoarthritis pathology

Francisco J. Blanco, Ram�n Guitian, Eduardo V�zquez-Martul et al. · Arthritis & Rheumatism · 1998 · 594 citations

Medicine, Cell Biology, Pathology +17