Role of urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitor type 1 (PAI-1) for prognosis in endometrial cancer

The serpin PAI-1 inhibits cell migration by blocking integrin αvβ3 binding to vitronectin

Steingrimur Stefansson, Daniel A. Lawrence · Nature · 1996 · 679 citations

Life Sciences, Cell Biology, Molecular Biology +12

Blaustein’s Pathology of the Female Genital Tract

Bruce A. Warren · Pathology · 1995 · 411 citations

Medicine, Gynecology, Pathology +14

High levels of urokinase-type plasminogen activator and its inhibitor PAI-1 in cytosolic extracts of breast carcinomas are associated with poor prognosis.

J Grøndahl-Hansen, I. J. Christensen, Christian Rosenquist et al. · PubMed · 1993 · 390 citations

Medicine, Cancer Biology, Oncology +13

Occupational exposure to heavy metals: DNA damage induction and DNA repair inhibition prove co-exposures to cadmium, cobalt and lead as more dangerous than hitherto expected

Jan G. Hengstler · Carcinogenesis · 2003 · 273 citations · Full text

Pharmacy, Environmental Sciences, Toxicology +13

ErbB-3 Predicts Survival in Ovarian Cancer

Berno Tanner, Dirk Hasenclever, Katja Stern et al. · Journal of Clinical Oncology · 2006 · 232 citations

Medicine, Gynecology, Oncology +17