Matrix Gla Protein Expression in NRK-52E Cells Exposed to Oxalate and Calcium Oxalate Monohydrate Crystals

Abstract

Our results have given a profile of MGP expression in renal tubular epithelial cells exposed to oxalate and crystals and provided support for an association between MGP and kidney stones. Further investigations on the mechanism of the MGP in the process of crystal-cell interaction may be important in the future.