Members of a nicotinic acetylcholine receptor gene family are expressed in different regions of the mammalian central nervous system

DNA sequencing with chain-terminating inhibitors

Frederick Sanger, S. Nicklen, Alan Coulson · Proceedings of the National Academy of Sciences · 1977 · 69.3K citations · Full text

Life Sciences, Microbiology, Molecular Biology +10

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

Haim Aviv, Philip Leder · Proceedings of the National Academy of Sciences · 1972 · 6.9K citations

Life Sciences, Biochemistry, Molecular Biology +10

Efficient<i>in vitro</i>synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

Douglas A. Melton, Paul A. Krieg, Michael R. Rebagliati et al. · Nucleic Acids Research · 1984 · 6.4K citations · Full text

Life Sciences, Biotechnology, Molecular Biology +11

A simple and very efficient method for generating cDNA libraries

Ueli Gubler, Beth J. Hoffman · Gene · 1983 · 4.6K citations

Life Sciences, Molecular Biology, Molecular Genetics +10

Colony hybridization: a method for the isolation of cloned DNAs that contain a specific gene.

Michael Grunstein, David S. Hogness · Proceedings of the National Academy of Sciences · 1975 · 3.5K citations · Full text

Life Sciences, Genetics, Microbiology +17