Dose dependency of earthworm powder on antithrombotic and fibrinolytic effects

Regulation of murine type 1 plasminogen activator inhibitor gene expression in vivo. Tissue specificity and induction by lipopolysaccharide, tumor necrosis factor-alpha, and transforming growth factor-beta.

Michael Sawdey, David J. Loskutoff · Journal of Clinical Investigation · 1991 · 410 citations · Full text

Tissue Specificity, Immunology, Pathology +20

Enhancement of the Fibrinolytic Activity in Plasma by Oral Administration of Nattokinase<sup>s</sup>

Hiroyuki Sumi, Hiroki Hamada, Kouichiro Nakanishi et al. · Acta Haematologica · 1990 · 305 citations

Fibrinolytic Activity, Immunology, Induced Thrombosis +17

A Novel Fibrinolytic Enzyme Extracted from the Earthworm, Lumbricus rubellus.

Hisashi Mihara, Hiroyuki Sumi, Tomoyuki Yoneta et al. · The Japanese Journal of Physiology · 1991 · 261 citations · Full text

Novel Fibrinolytic Enzymes, Biochemistry, Antiparasitic Agent +8

Effect of 1-Methyl-2-Mercapto-5-(3-Pyridyl)-Imidazole (KC-6141), an Anti-Aggregating Compound, on Experimental Thrombosis in Rats

T Umetsu, Kazuko Sanai · Thrombosis and Haemostasis · 1978 · 90 citations

Pharmacotherapy, Platelet Aggregation, Experimental Thrombosis +19

Chemical Modification of Earthworm Fibrinolytic Enzyme with Human Serum Albumin Fragment and Characterization of the Protease as a Therapeutic Enzyme

Nobuyoshi Nakajima, Kohji Ishihara, Manabu Sugimoto et al. · Bioscience Biotechnology and Biochemistry · 1996 · 47 citations · Full text