A Facile and Highly Efficient Route to a Traceless π-Arene Chromium Linker. Applications to Synthetic and Combinatorial Chemistry

Abstract

[reaction--see text] A simple and efficient method for the attachment of functionalized arene chromium carbonyls to a polymeric support has been developed. A highly efficient solid-phase synthesis of tertiary alcohols and esters was performed in a traceless manner using this strategy. The linker-fabrication protocol permits simultaneous immobilization of various substrates on the solid support.