Australian and New Zealand Journal of Surgery · 1995 · 28 citations · 15 references
MedicineOncologySurgeryGastrointestinal OncologyOncologic SurgerySurgical OncologyAdjuvant ChemotherapyAdjuvant TherapyColorectal CancerColorectal SurgeryConcurrent ChemoradiationAdjuvant Therapy After ResectionColorectal Cancer Adjuvant TherapyRectal Cancer RadiotherapyRectal Cancer SurgerySurgical Adjuvant Therapy
The morbidity of postoperative adjuvant chemoradiation for primary extraperitoneal rectal carcinoma is documented in this ongoing study. Patients who presented electively for resection with ACPS Dukes' B and C extraperitoneal rectal carcinoma during the period January 1990 to June 1993 were studied. Twenty patients received postoperative adjuvant chemoradiation. At a mean follow up of 32.6 months (s.d. 7.1), three of the 20 patients who received combined adjuvant chemoradiation reported no side effects. In 10 patients (50%) complications were classified as minor. In the remaining seven patients (35%) major complications of therapy occurred. There were no deaths. These early results highlight the morbidity of postoperative adjuvant chemoradiation that has been presumed but not documented.
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Effective Surgical Adjuvant Therapy for High-Risk Rectal Carcinoma
James E. Krook, C G Moertel, Leonard L. Gunderson et al. · New England Journal of Medicine · 1991 · 1.9K citations
Long-term functional results of coloanal anastomosis for rectal cancer
Philip B. Paty, Warren E. Enker, Alfred M. Cohen et al. · The American Journal of Surgery · 1994 · 171 citations