Rapid Prototyping Journal · 2001 · 95 citations · 2 references
EngineeringBiomedical EngineeringMaterials EngineeringBiomaterialsDrug DeliveryPharmaceutical ManufacturingDrug Delivery EngineeringDrug Delivery SystemsFabrication MaterialsPorosity CharacterizationPorous MaterialsSinteringDrug Delivery DevicesImplantable Drug Delivery DevicesMedication Delivery DevicesPorosityPorosity ControlPorosity EffectsPorous Material DesignPorous Structures
There are many applications for rapid prototyping systems and application in the biomedical field is an important domain. Uses selective laser sintering (SLS) in this study to build porous cylindrical disc matrices for use as drug delivery devices (DDD). Studies the part‐bed temperature to ascertain its influence over the porosity of the disc matrices. They are found to have an inverse linear relationship. Also investigates the dense walls, the inherent consequences of building porous structures with the SLS, in the disc matrix as they have a direct impact on the performance of the DDD. Discusses the size constraint of the disc matrix due to the limitations of the SLS process. Also investigates the possibility of creating disc matrices of varying porosity. Experimental results demonstrate that SLS is viable in producing DDDs that have variable porosity and micro‐features.
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Kah Fai Leong, Kok Khoo Phua, Chee Kai Chua et al. · Proceedings of the Institution of Mechanical Engineers Part H Journal of Engineering in Medicine · 2001 · 108 citations