Receptor mediated coated vesicle transport of rat IgG across the 11.5 day in vitro rat yolk sac endoderm

Abstract

Using colloidal gold as an electron dense marker we present evidence for the in vitro transport of rat IgG across the 11.5 day rat yolk sac endoderm. This process was receptor mediated and involved a population of coated vesicles. Two probes, protein-A colloidal gold and rat IgG colloidal gold, behaved differently in this culture system. The implication of this finding is discussed.