CHANGES IN BRAIN ACTIVITY FOLLOWING SACRAL NEUROMODULATION FOR URINARY RETENTION

Abstract

Our study provides novel neuroimaging evidence for the existence of abnormal interaction between brainstem and cortical centers in women with urinary retention. Furthermore, we have been able to show evidence that the therapeutic effect of sacral neuromodulation is achieved through restoration of activity associated with brainstem autoregulation and attenuation of cingulate activity.