Solubilization of Hemin in Neutral and Acidic Aqueous Solutions by Forming Complexes with Water-Soluble Macromolecules

Abstract

Abstract Hemin was solubilized in neutral and acidic aqueous solutions by complexing with poly(N-vinylpyrrolidone) (PVP), polyethylene glycol (PEG), poly(vinyl alcohol) (PVA) and dextran. In neutral aqueous solutions, hemin in the PVP, PEG, and PVA complexes was monomeric and that in the dextran complex was dimeric. The effects of pH and ultraviolet (UV) irradiation on the spectroscopic properties of the complexes were examined.