A pilot study of hepatic artery floxuridine combined with systemic 5-fluorouracil and leucovorin.A potential adjuvant program after resection of colorectal hepatic metastases

Abstract

Systemic 5-FU and LV can be combined safely with intraarterial FUDR without loss of efficacy or increased biliary toxicity. Eight patients treated with this regimen as adjuvant therapy after liver metastasis resection were alive and disease-free after a median follow-up of 23 months.