Journal of Labelled Compounds and Radiopharmaceuticals · 2001 · 12 citations · 2 references
MedicineNuclear MedicineRadiologyDiagnostic Nuclear MedicineDiagnostic RadiologyNuclear ChemistryNuclear Medicine ChemistryNuclear Medicine ImagingPositron Emission TomographyRadioisotope ProductionRadiopharmaceuticalsRadiotracer TechniquesPet RadiopharmaceuticalsRadiopharmaceutical PharmacokineticsRadiopharmaceutical PhysicsRadiopharmaceutical UptakeSingle-photon EmissionTc-99m Generator ProductionTechnetium-99m ChemistryTechnetium-99m Radiopharmaceuticals
Abstract Technetium‐99m is a widely used radioisotope in nuclear medicine. The characteristics of this generator‐produced radionuclide (T 1/2 = 6 h, Eγ = 140.5 keV, Iγ = 87.2 %) make it an ideal isotope for single photon emission computed tomography (SPECT). Technetium‐94m has a half‐life of 52 minutes and a positron branching ratio of 72 %, with E β+max of 2.44 MeV. Technetium‐94m undergoes the same chemistry as 99m Tc, but has characteristics suitable for imaging using positron emission tomography (PET), with which more quantitative measurements of radiopharmaceutical uptake, biodistribution and clearance can be made.
2
MicroPET: a high resolution PET scanner for imaging small animals
Simon R. Cherry, Yiping Shao, Robert W. Silverman et al. · IEEE Transactions on Nuclear Science · 1997 · 615 citations