Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer

A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif

Andrew Sinclair, Philippe Berta, Mark S. Palmer et al. · Nature · 1990 · 3.3K citations

Life Sciences, Genetics, Molecular Genetics +13

Male development of chromosomally female mice transgenic for Sry

Peter Koopman, John Gubbay, Nigel Vivian et al. · Nature · 1991 · 2.2K citations

Life Sciences, Developmental Biology, Genetics +14

A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes

John Gubbay, Jérôme Collignon, Peter Koopman et al. · Nature · 1990 · 1.7K citations

Life Sciences, Genetics, Molecular Genetics +13

A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiation

Xunrong Luo, Yayoi Ikeda, Keith L. Parker · Cell · 1994 · 1.6K citations

Life Sciences, Developmental Biology, Endocrinology +16

Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene

Jamie W. Foster, M. Dominguez-Steglich, Silvana Guioli et al. · Nature · 1994 · 1.6K citations

Life Sciences, Genetics, Molecular Genetics +13