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Insertional inactivation of the large subunit of ribonucleotide reductase encoded by vaccinia virus is associated with reduced virulence in vivo

VaccinationVirus StructureViral ReplicationMolecular VirologyNatural SciencesPathogenesisReduced VirulenceDna ReplicationVirologyMolecular BiologyInsertional InactivationMicrobiologyMedicineVirus GeneViral GeneticsVaccinia Virus