Trends in HIV-1 Incidence in a Cohort of Prostitutes in Kenya: Implications for HIV-1 Vaccine Efficacy Trials

Abstract

This study documents a dramatic decline in the risk of HIV-1 infection while participating in a prospective cohort, with most seroconversions occurring within 1 year of enrollment. Variations in HIV-1 incidence within high-risk populations should be anticipated during the design of vaccine trials.