DO CD4-POSITIVE CYTOTOXIC T CELLS DAMAGE ISLET β CELLS IN TYPE 1 DIABETES?

ROLE OF ABERRANT HLA-DR EXPRESSION AND ANTIGEN PRESENTATION IN INDUCTION OF ENDOCRINE AUTOIMMUNITY

GianFranco Bottazzo, Toshiaki Hanafusa, Ricardo Pujol‐Borrell et al. · The Lancet · 1983 · 1.3K citations

Life Sciences, Endocrinology, Immunology +10

In Situ Characterization of Autoimmune Phenomena and Expression of HLA Molecules in the Pancreas in Diabetic Insulitis

Gian Franco Bottazzo, B.M. Dean, Jessica M. McNally et al. · New England Journal of Medicine · 1985 · 937 citations

Life Sciences, Immunology, Pathology +17

HLA class II induction in human islet cells by interferon-γ plus tumour necrosis factor or lymphotoxin

Ricardo Pujol‐Borrell, Ian Todd, Mala Doshi et al. · Nature · 1987 · 446 citations

Life Sciences, Endocrinology, Immunology +16

Epstein-Barr Virus: Transformation, Cytopathic Changes, and Viral Antigens in Squirrel Monkey and Marmoset Leukocytes

George Miller, Thomas C. Shope, Hermann Lisco et al. · Proceedings of the National Academy of Sciences · 1972 · 442 citations

Life Sciences, Cell Biology, Infectious Diseases +10

Large-Scale Purification of Human Islets Utilizing Discontinuous Albumin Gradient on IBM 2991 Cell Separator

Stephen P. Lake, P Drew Bassett, Audrey Larkins et al. · Diabetes · 1989 · 213 citations

Pharmacy, Cell Biology, Endocrinology +16