A field investigation of kennel cough: Efficacy of vaccination

Abstract

ABSTRACT A case‐control study was conducted to investigate the efficacy of several vaccines in protecting against canine kennel cough. Cases and controls were selected from a random sample of veterinary practices in the UK, and relevant information was collected using postal questionnaires. The relationship between vaccinal status and the occurrence of kennel cough was examined using a linear logistic model. Vaccination against Bordetella bronchiseptica and canine parainfluenza virus was associated with reduced risks of the disease, as indicated by a decrease in the log odds (log relative risk) of disease in vaccinated animals, when integrated with usual vaccination strategies. Statistical interaction between these two vaccines and adenovirus vaccines was identified.