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Synthesis of labelled ecdysone precursors: Part I‐tritium labelled (<sup>3</sup>H<sub>4</sub>‐22, 23,24,25)‐3β, 14α‐dihydroxy‐5β‐cholest‐7‐en‐6‐one
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Citations
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References
1985
Year
BiosynthesisEngineeringBiochemistryNatural SciencesEasy LabellingLabelled Ecdysone PrecursorsInsect Prothoracic GlandsEcdysone BiosynthesisNatural Product BiosynthesisOrganic ChemistryChemistryChemical BiologyNatural Product SynthesisPart I‐tritiumSynthetic ChemistryEnantioselective SynthesisBiomolecular Engineering
Abstract High specific activity tritiated 3β, 14α ‐dihydroxy‐5β‐cholest‐7‐en‐6‐one, has been prepared using a precursor which permits rapid and easy labelling. This compound is converted to ecdysone under in vitro conditions by insect prothoracic glands, a well known site of ecdysone biosynthesis.
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