Evidence-based Complementary and Alternative Medicine · 2014 · 88 citations · 38 references
MedicinePlastic SurgerySurgeryHemostasisMicrosurgeryReconstructive SurgeryAmputationThrombosisHemoglobin FunctionLeech TherapyVenous ReturnWound Necrosis
A written informed consent should be obtained from the patient before hirudotherapy is initiated. The patients should be treated each day of leech therapy with anti-Aeromonas antibiotics. Leeches should be applied on the darker spots of the reattached body parts or flaps. Usually 1-10 leeches are used for each treatment, while at the beginning, the patient might need two or more treatments per day. Leech therapy is used until venous capillary return is established across the wound border by angiogenesis. Usually the treatment with leeches lasts for 2-6 days. Hematologic evaluations should be performed every 4 hrs and the patient has to receive blood transfusions when the hemoglobin level is lower than 8 g/dL. Signs of regional lymphadenitis, slight swelling, and pain of regional lymph nodes on the side of leech application and subfebrile temperature can occur. Contraindications related to hirudotherapy include arterial insufficiency, hemophilia, hemorrhagic diathesis, hematological malignancies, anemia, hypotension, and sepsis. Leech therapy is not recommended in pregnancy and lactation and in patients with an unstable medical status, history of allergy to leeches or severe allergic diathesis, and disposition to keloid scar formation, as well as in those using anticoagulants and immunosuppressants.
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Mark E. Siddall, Peter Trontelj, Serge Utevsky et al. · Proceedings of the Royal Society B Biological Sciences · 2007 · 169 citations · Full text
Hirudo Medicinalis and the plastic surgeon
Iain S. Whitaker, David Izadi, David W. Oliver et al. · British Journal of Plastic Surgery · 2004 · 137 citations
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Andreas Michalsen, Stefanie Klotz, Rainer Ldtke et al. · Annals of Internal Medicine · 2003 · 133 citations
Microsurgical Reattachment of Totally Amputated Ears
Keith L. Mutimer, Joseph C. Banis, Joseph Upton et al. · Plastic & Reconstructive Surgery · 1987 · 118 citations
Medicine, Otolaryngology, Surgery +13