Complex interactions between pregnenolone sulfate and the t-butylbicyclophosphorothionate-labeled chloride ionophore in rat brain

Steroid Hormone Metabolites Are Barbiturate-Like Modulators of the GABA Receptor

Maria Dorota Majewska, Neil L. Harrison, Rochelle D. Schwartz et al. · Science · 1986 · 2.2K citations

Medicine, Neuroscience, Pharmacology +17

Structure-activity relationships for steroid interaction with the gamma-aminobutyric acidA receptor complex.

Neil L. Harrison, Monika Majewska, J W Harrington et al. · Journal of Pharmacology and Experimental Therapeutics · 1987 · 615 citations

Life Sciences, Neuroscience, Pharmacology +17

[35S]t-butylbicyclophosphorothionate binds with high affinity to brain-specific sites coupled to gamma-aminobutyric acid-A and ion recognition sites.

Richard F. Squires, John E. Casida, Michael Richardson et al. · Molecular Pharmacology · 1983 · 552 citations

Life Sciences, Neuroscience, Pharmacology +11

Steroid modulation of the chloride ionophore in rat brain: structure-activity requirements, regional dependence and mechanism of action.

Kelvin W. Gee, Michael B. Bolger, Roberta Dı́az Brinton et al. · Journal of Pharmacology and Experimental Therapeutics · 1988 · 467 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Pregnenolone and its sulfate ester in the rat brain

Colette Corpéchot, Monique Synguélakis, Saliha Talha et al. · Brain Research · 1983 · 387 citations

Life Sciences, Neurobiology, Neuroscience +11