Copper(I) oxide and benzoic acid ‘on water’: a highly practical and efficient catalytic system for copper(I)-catalyzed azide–alkyne cycloaddition

A Stepwise Huisgen Cycloaddition Process: Copper(I)-Catalyzed Regioselective “Ligation” of Azides and Terminal Alkynes

Vsevolod V. Rostovtsev, Luke G. Green, Valery V. Fokin et al. · Angewandte Chemie International Edition · 2002 · 11.4K citations

Terminal Alkynes, Chemical Engineering, Novel Organocatalysts +12

Peptidotriazoles on Solid Phase:  [1,2,3]-Triazoles by Regiospecific Copper(I)-Catalyzed 1,3-Dipolar Cycloadditions of Terminal Alkynes to Azides

Christian W. Tornøe, Caspar Christensen, Morten Meldal · The Journal of Organic Chemistry · 2002 · 8.4K citations

Terminal Alkynes, Novel Organocatalysts, Solid Phase +15

Polytriazoles as Copper(I)-Stabilizing Ligands in Catalysis

Timothy R. Chan, Robert Hilgraf, K. Barry Sharpless et al. · Organic Letters · 2004 · 1.5K citations

Inorganic Chemistry, Chemical Engineering, Powerful Stabilizing Ligand +8

Cu^I‐Catalyzed Alkyne–Azide “Click” Cycloadditions from a Mechanistic and Synthetic Perspective

Victoria D. Bock, Henk Hiemstra, Jan H. van Maarseveen · European Journal of Organic Chemistry · 2005 · 1.4K citations

Chemical Engineering, Cross-coupling Reaction, Engineering +10

Ligand-Accelerated Cu-Catalyzed Azide−Alkyne Cycloaddition:  A Mechanistic Report

Valentin O. Rodionov, Stanislav I. Presolski, David Díaz Díaz et al. · Journal of the American Chemical Society · 2007 · 396 citations

Electron Density, Engineering, Heterocyclic +11