Concepedia

Activation of purified guanylate cyclase by nitric oxide requires heme comparison of heme-deficient, heme-reconstituted and heme-containing forms of soluble enzyme from bovine lung

Louis J. Ignarro, Jonathan N. Degnan, William H. Baricos, Philip J. Kadowitz, Michael S. Wolin

Biochimica et Biophysica Acta (BBA) - General Subjects · 1982 · 263 citations · 19 references

DOI

Concepts

References

19

Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates.

L J Ignarro, Howard Lippton, Jo C. W. Edwards et al. · Journal of Pharmacology and Experimental Therapeutics · 1981 · 1.6K citations

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Evidence for the inhibitory role of guanosine 3', 5'-monophosphate in ADP-induced human platelet aggregation in the presence of nitric oxide and related vasodilators

BT Mellion, L J Ignarro, E H Ohlstein et al. · Blood · 1981 · 633 citations · Full text

, , +16

Soluble guanylate cyclase purified from bovine lung contains heme and copper

R. Gerzer, Eycke Böhme, Franz Hofmann et al. · FEBS Letters · 1981 · 328 citations · Full text

, , +6

Restoration of the responsiveness of purified guanylate cyclase to nitrosoguanidine, nitric oxide, and related activators by heme and hemeproteins. Evidence for involvement of the paramagnetic nitrosyl-heme complex in enzyme activation.

Patricia A. Craven, Frederick R. DeRubertis · Journal of Biological Chemistry · 1978 · 326 citations · Full text

, , +13

Methylene blue inhibits coronary arterial relaxation and guanylate cyclase activation by nitroglycerin, sodium nitrite, and amyl nitrite

Carl A. Gruetter, Philip J. Kadowitz, Louis J. Ignarro · Canadian Journal of Physiology and Pharmacology · 1981 · 316 citations

, , +14