Palladium-catalyzed Hiyama coupling reaction of arylsulfonyl hydrazides under oxygen

Abstract

Palladium-catalyzed Hiyama cross-coupling reactions of various arylsulfonyl hydrazides with a wide variety of aryl silanes have been achieved in good to excellent yields under simple conditions. The newly developed catalytic system does not require the use of expensive silver- or copper-based stoichiometric oxidants and can be accelerated by the addition of TBAT under an atmosphere of oxygen. The reported Hiyama-type coupling reactions are tolerant to common functional groups, making these transformations attractive alternatives to the traditional cross-coupling approaches.