Activin and transforming growth factor-β signaling pathways are activated after allergen challenge in mild asthma

Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors

Marie‐José Goumans · The EMBO Journal · 2002 · 1.1K citations · Full text

Endothelial Cell Pathobiology, Activation State, Molecular Physiology +13

Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma.

Qutayba Hamid, May Azzawi, Redwan Moqbel et al. · Journal of Clinical Investigation · 1991 · 846 citations · Full text

Asthma, Inflammatory Lung Disease, Laboratory Immunology +18

Cloning of a TGF$beta; type I receptor that forms a heteromeric complex with the TGF$beta; type II receptor

Petra Franzèn · Cell · 1993 · 770 citations · Full text

Signal Transduction, Molecular Physiology, G Protein-coupled Receptor +7

Activin Receptor-like Kinase (ALK)1 Is an Antagonistic Mediator of Lateral TGFβ/ALK5 Signaling

Marie‐José Goumans, Guðrún Valdimarsdóttir, Susumu Itoh et al. · Molecular Cell · 2003 · 684 citations · Full text

Lateral Tgfβ/alk5, Activin Receptor-like Kinase, Signal Transduction +9

Activation of CD4+ T cells, increased TH2-type cytokine mRNA expression, and eosinophil recruitment in bronchoalveolar lavage after allergen inhalation challenge in patients with atopic asthma

Q Hamid, Andrew Bentley, Sun Ying et al. · Journal of Allergy and Clinical Immunology · 1993 · 585 citations · Full text