Hemodynamic Adaptations in Different Trimesters Among Nulliparous and Multiparous Pregnant Women; The Generation R Study

Abstract

Nulliparous pregnant women have higher blood pressure levels throughout pregnancy and higher risks of notching and gestational hypertensive disorders. The first pregnancy might be a major risk factor for maternal hemodynamic maladaptations and vascular complications. Further studies are needed to explore the underlying mechanisms and consequences for fetal growth and development.