Canadian Journal of Fisheries and Aquatic Sciences · 1987 · 205 citations · 13 references
MedicineBiochemistryPhysiologyFish BiologyFish PhysiologyMineral MetabolismCopper ToxicityElectrolyte BalanceElectrolyte HomeostasisHeavy Metal BioaccumulationSodium BalanceSodium HomeostasisBody Sodium StoresCopper Efflux MechanismsCopper Exposure EffectsCopper KineticsCopper Uptake MechanismsEnvironmental Copper ExposureSodium Exchange KineticsSodium Uptake Dynamics
Juvenile rainbow trout (Salmo gairdneri) were exposed to 55 μg copper∙L −1 for 28 d and then transferred to uncontaminated water for 7 d. Whole body sodium concentration and sodium uptake (J in ) were measured at weekly intervals; J in was measured at various Na + concentrations and kinetic parameters estimated. After 24 h of copper exposure, the maximum rate of sodium uptake (J max ) was inhibited by 55%, the affinity for sodium (K m ) reduced by 49%, and whole body Na + decreased by about 12.5%. After 7 d of exposure, whole body Na + had returned to control values, but J max was still inhibited by 41%. Recovery of whole body Na + occurred largely by a reduction of sodium efflux (J out ). Both J max and K m continued to recover until day 28, at which time J in had returned to control values. We conclude that acclimation to sublethal copper depends on changes in both Na + transport and permeability.
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