Marine Drugs · 2009 · 34 citations · 10 references
Natural SciencesBiochemistryChemistryDrug DiscoveryMarine MicrobiologyStructure-activity RelationshipsBioinorganic ChemistryMarine Bioactive CompoundsMarine Drug DiscoveryMarine Fish BiologyMarine Microbial BiotechnologyMarine Natural ProductsBioactive Compounds From Marine EchinodermsBioactive Compounds From Marine FungiBioactive Marine MetabolitesChemical TransformationMarine BiodiscoveryMarine Compound Structure ElucidationMarine-derived Anticancer CompoundsMarine-derived Drug Discovery
Seco-chaetomugilins A and D were isolated from a strain of Chaetomium globosum that was originally isolated from the marine fish Mugil cephalus, and their absolute stereostructures were elucidated on the basis of spectroscopic analyses, including 1D and 2D NMR techniques, along with the chemical transformation from known chaetomugilins A and D. Seco-chaetomugilin D exhibited growth inhibitory activity against cultured P388, HL-60, L1210, and KB cells.
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Cytotoxic cytochalasans from a Penicillium species separated from a marine alga
Chika Iwamoto, Takeshi Yamada, Yoshinori Ito et al. · Tetrahedron · 2001 · 102 citations
Life Sciences, Botany, Microbiology +12
Takeshi Yamada, Masashi Iritani, Mitsunobu Doi et al. · Journal of the Chemical Society Perkin Transactions 1 · 2001 · 81 citations