(<i>S</i>)-(+)-4-[7-(2,2-Dimethyl-1-oxopro- poxy)-4-methyl-2-[4-[2-(1-piperidinyl)- ethoxy]phenyl]-2<i>H</i>-1-benzopyran-3-yl]- phenyl 2,2-Dimethylpropanoate (EM-800): A Highly Potent, Specific, and Orally Active Nonsteroidal Antiestrogen

Abstract

ADVERTISEMENT RETURN TO ISSUEPREVLetterNEXT(S)-(+)-4-[7-(2,2-Dimethyl-1-oxopro- poxy)-4-methyl-2-[4-[2-(1-piperidinyl)- ethoxy]phenyl]-2H-1-benzopyran-3-yl]- phenyl 2,2-Dimethylpropanoate (EM-800): A Highly Potent, Specific, and Orally Active Nonsteroidal AntiestrogenSylvain Gauthier, Brigitte Caron, Julie Cloutier, Yves L. Dory, Alexandre Favre, Denis Larouche, Josée Mailhot, Carl Ouellet, Annette Schwerdtfeger, Gilles Leblanc, Céline Martel, Jacques Simard, Yves Mérand, Alain Bélanger, Claude Labrie, and Fernand LabrieView Author Information Laboratory of Molecular Endocrinology, CHUL Research Centre, Le Centre Hospitalier Universitaire de Québec and Laval University, Québec, G1V 4G2, Canada Cite this: J. Med. Chem. 1997, 40, 14, 2117–2122Publication Date (Web):July 4, 1997Publication History Received14 February 1997Published online4 July 1997Published inissue 1 July 1997https://pubs.acs.org/doi/10.1021/jm970095ohttps://doi.org/10.1021/jm970095orapid-communicationACS PublicationsCopyright © 1997 American Chemical SocietyRequest reuse permissionsArticle Views854Altmetric-Citations126LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Cancer,Cell physiology,Inhibition,Receptors,Rodent models Get e-Alerts