Nuclear Factor‐Kappa B Activation in the Nasal Polyp Epithelium: Relationship to Local Cytokine Gene Expression

Abstract

The activation of NF-kappaB in the nasal polyp epithelium is responsible for the recruitment of inflammatory cells, particularly eosinophils, through the initiation of the transcriptional pathway of the related cytokines. The increased NF-kappaB activity in the polyp epithelium may reflect hypersensitivity to unknown stimuli.