Room-Temperature Kumada Cross-Coupling of Unactivated Aryl Chlorides Catalyzed by <i>N</i>-Heterocylic Carbene-Based Nickel(II) Complexes

Abstract

The Kumada cross-coupling reaction of a variety of unactivated aryl chlorides, vinyl chlorides, and heteroaryl chlorides catalyzed by nickel(II) complexes containing pyridine-functionalized NHC ligands is described. The catalysts are so active that the reactions proceed at room temperature in excellent yields.