genesis · 2000 · 182 citations · 12 references
Life SciencesGeneticsMolecular GeneticsGene ExpressionMolecular NeuroscienceNeurogeneticsCalcium SignalingGene Expression In NeuronsMolecular NeurogeneticsNeural DevelopmentTransgene ConstructionTransgene Expression ControlBrain Region-specific TransgenesisCalcium-calmodulin SignalingCalcium-dependent Protein Kinase IiCalmodulin-dependent Protein Kinase IiCre-dependent Reporter SystemsCre-lox Recombination SystemsInducible Transgene ExpressionTransgene Expression
An 8.5 kb 5flanking genomic fragment of the alpha subunit of the calcium/calmodulin-dependent protein kinase II gene (CaMKII) has been shown to confer brain specific expression on a variety of transgenes in the mouse, including Cre recombinase (Mansuy et al.,
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Manipulating the mouse embryo: A laboratory manual
Martin Johnson · Trends in Genetics · 1986 · 2.3K citations
Veterinary Medicine, Cell Biology, Developmental Biology +12
Deletion of a DNA Polymerase β Gene Segment in T Cells Using Cell Type-Specific Gene Targeting
Hua Gu, Jamey D. Marth, Paul C. Orban et al. · Science · 1994 · 1.4K citations
Subregion- and Cell Type–Restricted Gene Knockout in Mouse Brain
Joe Z. Tsien, Dong Feng Chen, David J. Gerber et al. · Cell · 1996 · 1.3K citations · Full text