Acta Paediatrica · 2009 · 178 citations · 16 references
MedicineNutritionPediatricsInfant FeedingInfant HealthPediatric NutritionInfant Feeding PracticesInfant NutritionNeonatal DevelopmentNeonatal NutritionNeonatal PhysiologyNewborn PhysiologyEarly Feeding PhysiologyInfant Feeding PatternsInfant RegurgitationInfant Weight LossPremature Infant Feeding
OBJECTIVES: To determine the natural history of infant regurgitation during the first year of life. METHODS: Parents recorded prospectively the frequency of regurgitation for 1 week before consultation during the first year of life. A sub-group analysis according to the method of feeding was planned. RESULTS: A total of 130 infants of an original sample of 163 (80%) newborns were followed up for 1 year. Daily spilling was highest during the first month of life (73%) and decreased gradually to 50% during the fifth month of life. During the first 2 months of life, 20% of the infants regurgitated more than four times per day. After the age of 12 months, only 4% of the infants had daily regurgitations. Exclusively breastfed infants did regurgitate less than partially breastfed infants. Weight gain was influenced by the frequency of regurgitation, especially in partially breastfed infants. CONCLUSION: Regurgitation in infancy is common, decreasing from birth, and tends to disappear by 12 months of age. Weight gain during the first 4 months of life is decreased in infants who regurgitate more than four times a day. Our data suggest that exclusively breastfed infants regurgitate less than partially breastfed babies.
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Natural History and Familial Relationships of Infant Spilling to 9 Years of Age
Anne Martin, Nicole Pratt, J.D. Kennedy et al. · PEDIATRICS · 2002 · 263 citations
Proton Pump Inhibitor Utilization Patterns in Infants
John J. Barron, Hiangkiat Tan, James Spalding et al. · Journal of Pediatric Gastroenterology and Nutrition · 2007 · 240 citations