Concepedia

Discovery and pharmacological characterization of aryl piperazine and piperidine ethers as dual acting norepinephrine reuptake inhibitors and 5-HT1A partial agonists

David Gray, Wenjian Xu, Brian Campbell, Amy B. Dounay, Nancy S. Barta, Susan Boroski, Lynne Denny, Lori M. Evans, Nancy C. Stratman, Al Probert

Bioorganic & Medicinal Chemistry Letters · 2009 · 15 citations · 21 references

Open access

Concepts

PharmacyMedicinal ChemistryPharmacologyDrug DiscoveryNeuropharmacologyStructure-activity RelationshipsSerotonergic PharmacologyStructure-activity Relationship Analysis5-Hydroxytryptamine 1A Receptor Agonists5-Hydroxytryptamine Receptor PharmacologyNorepinephrine Reuptake InhibitionPharmacological ProfilingPharmacological ScreeningPiperidine ChemistrySerotonergic Drug Discovery

References

21

The Pharmacological Basis of Therapeutics

American Journal of Health-System Pharmacy · 1976 · 8.2K citations

Medicine, Pharmacology, Pharmacotherapy +10

The pharmacological basis of therapeutics

Joy Davies · Occupational and Environmental Medicine · 2007 · 576 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +10

N-Desalkylquetiapine, a Potent Norepinephrine Reuptake Inhibitor and Partial 5-HT1A Agonist, as a Putative Mediator of Quetiapine's Antidepressant Activity

Niels Jensen, Ramona M. Rodriguiz, Marc G. Caron et al. · Neuropsychopharmacology · 2007 · 313 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Ullmann Diaryl Ether Synthesis: Rate Acceleration by 2,2,6,6-Tetramethylheptane-3,5-dione

Elizabeth Buck, Zhiguo J. Song, David M. Tschaen et al. · Organic Letters · 2002 · 298 citations

Natural Sciences, Chemistry, Catalysis +14

Biospectra Analysis: Model Proteome Characterizations for Linking Molecular Structure and Biological Response

Anton Fliri, William Loging, Peter F. Thadeio et al. · Journal of Medicinal Chemistry · 2005 · 92 citations

Pharmacy, Biochemistry, Pharmacology +14