Epigenetic dysregulation of HTR2A in the brain of patients with schizophrenia and bipolar disorder

A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands.

Marianne Frommer, Louise E. McDonald, David Millar et al. · Proceedings of the National Academy of Sciences · 1992 · 3.3K citations

Life Sciences, Genetics, Molecular Biology +14

The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores

Rafael A. Irizarry, Christine Ladd‐Acosta, Bo Wen et al. · Nature Genetics · 2009 · 2.2K citations · Full text

Life Sciences, Molecular Biology, Oncology +16

Reelin promoter hypermethylation in schizophrenia

Dennis R. Grayson, Xiaomei Jia, Ying Chen et al. · Proceedings of the National Academy of Sciences · 2005 · 552 citations

Life Sciences, Genetics, Neuroscience +16

Hypomethylation of MB-COMT promoter is a major risk factor for schizophrenia and bipolar disorder

Hamid M. Abdolmaleky, Kuang‐Hung Cheng, Stephen V. Faraone et al. · Human Molecular Genetics · 2006 · 460 citations · Full text

Life Sciences, Genetics, Psychiatry +12

Hypermethylation of the reelin (<i>RELN</i>) promoter in the brain of schizophrenic patients: A preliminary report

Hamid M. Abdolmaleky, Kuang‐Hung Cheng, Andrea Russo et al. · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · 2005 · 388 citations

Life Sciences, Genetics, Neuroscience +17