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Chronopharmacokinetics of beta-receptor blocking drugs of different lipophilicity (propranolol, metoprolol, sotalol, atenolol) in plasma and tissues after single and multiple dosing in the rat

Pharmacological StudyMultiple DosingMedicinePhysiologyPharmacological AgentExperimental PharmacologyPharmacotherapyEndocrinologyPharmacologyPharmacokineticsDrug DiscoveryDifferent Lipophilicity