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A yeast artificial chromosome covering the tyrosinase gene confers copy number-dependent expression in transgenic mice

Yeast Artificial ChromosomeEngineeringGeneticsTyrosinase Gene ConfersGenomic MechanismGenetic EngineeringGenetic MechanismYeastMolecular GeneticsGenome EngineeringChromosomal RearrangementTransgenic MiceSystems BiologyMedicineGene ExpressionGenome EditingMutagenesis