Evaluation of <scp>d</scp> -Methionine as a Novel Oral Radiation Protector for Prevention of Mucositis

Abstract

D-Met protected normal tissues, but not tumor cells, in culture from radiation-induced cell death; it also protected normal cells from radiation-induced mucosal injury in a murine model but did not alter tumor response to therapy. Further studies on the use of D-Met to protect from oral mucositis are warranted.