The American Journal of Surgical Pathology · 1981 · 55 citations · 0 references
MedicineOncologyPathologyMetastasisNeoplasiaTumor PathologyEndocrine Tumor PathologyEndocrine TumorsGastric CancerGastric DiseasesGastrointestinal Cancer SurgeryGastrointestinal PathologyGastrointestinal MalignancyGastrointestinal TumorsImmunohistochemical BiomarkersImmunohistochemical DetectionImmunohistochemical MarkersImmunohistochemical StainingPathology Of Gastric Cancer
Two cases of extragenital choriocarcinoma arising in association with gastric adenocarcinoma are described. Using immunohistochemical methods, cells containing human chorionic gonadotropin, beta-subunit (hCG-beta) were localized exclusively to the choriocarcinomatous portion of the tumor. One patient whose tumor appeared to confined to the stomach at the time of surgery, had elevated serum hCG-beta postoperatively. Metastases became evident subsequently.