Four ingol type diterpenes from Euphorbia antiquorum L.

Abstract

From the latex of Euphorbia antiquorum L. (Euphorbiaceae), four macrocyclic diterpenes, 3, 12-di-O-acetyl-8-O-benzoylingol (1), 3, 12-di-O-acetly-8-O-tigloylingol (2), 12-O-acetyl-8-O-tigloylingol (3) and 8-O-tigloylingol (4), were isolated and characterized. Compound 1 was previously reported as a component of a mixture, but was obtained in pure form in this experiment. Compounds 3 and 4 were isolated for the first time from a natural source.